Sequencing Services

We provide full NGS service starting with support in study design, through sample preparation and sequencing, and ending with data analysis.  We also offer a ‘sequencing-only’ option for researchers who already have their libraries ready and/or prefer to do their own analysis.

Genomics

• Targeted high coverage sequencing
• Whole exome sequencing
• Whole genome sequencing

Transcriptomics

• 3’mRNAseq for quantification
• Full length mRNAseq for isoform and splicing events detection
• Total RNAseq includes non-coding RNA sequencing

Epigenomics

• Chromatin immunoprecipitation sequencing (ChIP-seq, Cut & Taq)
• Assay for transposase-accessible chromatin sequencing (ATAC-seq)

Metagenomics

• Shotgun and targeted (marker gene) sequencing to analyze total genetic content of a sample, revealing its composition and diversity

Single cell sequencing

• Nucleic acid sequencing at single cell resolution

Long-read sequencing

Short-read NGS (srNGS) methods can only sequence short DNA/RNA fragments which are then reassembled to create a longer sequence.  This limits their use for genomic regions of high homology (gene families, pseudogenes) or low complexity (repeat regions), differentiation of isoforms or high resolution of large structural variants. Nanopore sequencing can overcome these limitations with read lengths extending into megabases, allowing in-depth exploration of repetitive regions and complex structural variants, as well as differentiation between different isoforms. In addition, its ability to sequence native DNA/RNA eliminates PCR bias and allows for the identification of base modifications, such as methylation, alongside nucleotide sequence.